Do you have a special room set aside? Are you a "couch schooler"? Do you move around the house all day long? Is your kitchen table covered with books, science equipment and crafts?
I have five kids, from an 11th grader down to pre-schooler, and we homeschool in just about every room of the house.
My oldest does most of his schooling on the computer in an alcove off the living room. He usually has his his MP3 player and headphones on listening to music like classical, musicals or Christian rock. So, he usually doesn't hear what's going on around him. He does Geometry usually at the dining room table and he practices for speeches and plays in his bedroom.
My 9th grader likes to do most of his school in our small office at his school desk where he keeps his books. Sometimes he migrates out the the couch, kitchen island or his bedroom. Often he'll need the internet for research and he'll wait till his brother is finished, then he'll use the computer in the living room.
Isaiah(6th grade) and Christian (2nd grade) do half of their schoolwork at the dining room table, and half on the living room couch. I spend most of my morning working with them. They keep their school work in tubs on the school bookcase that is in the dining room. Sophie, my almost 3 yr. old, is usually at the table with us (or her picnic table that's also in the dining room) playing with playdough, coloring, using math blocks, sticker books, ect.
Science experiments, crafts and baking are usually done at the kitchen island or dining room table. When the warm weather gets here we often bring our books out to the deck, or sometimes even to a park.
When my kids were younger, our school was very different. We did more unit studies, and we did more projects and hands-on learning. I also did much of the teaching with all of them together. We also used Sonlight curriculum for many years and that involved lots of reading aloud on the couch (or outside during warm weather).